With heart failure, Lasix buy http://canadaslim.net/buy-lasix/ quickly reduces preload (by expanding the veins), reduces pulmonary artery pressure and the filling pressure of the left ventricle. This rapidly developing effect appears to be mediated through the effects of prostaglandins and therefore the condition for its development is the absence of disturbances in the synthesis of prostaglandins, in addition to which this effect also requires sufficient preservation of kidney function. The drug has an antihypertensive effect, which is caused by increased sodium excretion, a decrease in the volume of circulating blood, and a decrease in the response of the smooth muscles of the vessels to vasoconstrictor effects (due to the natriuretic effect, furosemide decreases the vascular response to catecholamines, whose concentration in hypertensive patients is increased).
Dose-dependent diuresis and natriuresis is observed when taking Lasix at a dose of 10 mg to 100 mg. (Healthy volunteers). After intravenous administration of 20 mg of Lazix, the diuretic effect develops after 15 minutes and lasts for about 3 hours.
 

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